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Baked casserole in a white dish with a golden brown breadcrumb topping, featuring visible spinach and artichoke pieces. A serving spoon is lifting a portion.
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Chicken Spinach and Artichoke Casserole

This creamy spinach artichoke chicken casserole recipe is an easy casserole packed with tender chicken, cheese, spinach, and flavor.
Prep Time20 minutes
Cook Time40 minutes
Total Time1 hour
Course: Casserole, Dinner
Cuisine: American
Servings: 6
Calories: 841kcal
Author: Wendy

Equipment

  • 2 large mixing bowls
  • 9x13 inch baking dish
  • spatula

Ingredients

  • 4 chicken breasts Boneless skinless , cooked and diced
  • 14 ounces artichoke hearts drained and chopped
  • 10 ounces frozen chopped spinach thawed and drained
  • 1 cup mayonnaise
  • 1 cup sour cream
  • 1 cup Parmesan cheese
  • 2 cups mozzarella cheese divided
  • 3 cloves garlic minced
  • 1 teaspoon dried oregano
  • 1 teaspoon onion powder
  • Salt and pepper to taste
  • 1 cup breadcrumbs optional, for topping

Instructions

  • Preheat the oven to 375°F (190°C). Grease a 9x13-inch baking dish.
  • In a large mixing bowl, combine the shredded chicken, chopped artichokes, and drained spinach.
  • In a separate bowl, mix together mayonnaise, sour cream, Parmesan cheese, 1 cup of mozzarella cheese, minced garlic, dried oregano, onion powder, salt, and pepper.
  • Add the creamy mixture to the chicken and vegetables, stirring until everything is well-coated.
  • Transfer the mixture to the prepared baking dish, spreading it evenly. Top with the remaining cheese.
  • If desired, sprinkle breadcrumbs over the top for a crunchy finish.
  • Bake in the preheated oven for 35-40 minutes or until the casserole is bubbly and golden brown on top.
  • Remove from the oven and let it rest for a few minutes before serving.

Nutrition

Serving: 1g | Calories: 841kcal | Carbohydrates: 23g | Protein: 52g | Fat: 59g | Saturated Fat: 18g | Polyunsaturated Fat: 18g | Monounsaturated Fat: 13g | Trans Fat: 0.1g | Cholesterol: 176mg | Sodium: 1440mg | Potassium: 869mg | Fiber: 4g | Sugar: 4g | Vitamin A: 6899IU | Vitamin C: 19mg | Calcium: 552mg | Iron: 3mg