15 Meatloaf Recipes That Shake Things Up

Meatloaf doesn’t have to be boring, and this lineup proves it. These recipes go beyond the usual ketchup-glazed loaf, offering stuffed versions, regional twists, low-carb ideas, and even plant-based alternatives. Some pack in bold seasonings, others layer in cheese, vegetables, or rich sauces, but every one offers something a little different. Whether you’re after something comforting and traditional or ready to try a smoky BBQ or taco-spiced variation, this list covers every angle of what meatloaf can be. Easy to slice, make ahead, and pair with sides, these meatloaf recipes bring the flavor without the fuss.

Taco Meatloaf

This version swaps out traditional spices for taco seasoning, turning your loaf into a Tex-Mex-inspired dinner. Salsa or enchilada sauce may replace ketchup, and crushed tortilla chips often stand in for breadcrumbs. Each slice is bold, hearty, and just a little spicy. Great with rice or a scoop of guacamole.
Get the Recipe: Taco Meatloaf

Easy Vegan Lentil Meatloaf Recipe

Made with lentils, oats, and vegetables, this loaf holds together well and bakes up with a classic tomato glaze. The texture is soft but sliceable, and the flavor is rich with herbs and garlic. It’s a satisfying plant-based take that still feels like comfort food. Ideal for serving with mashed potatoes or greens.
Get the Recipe: Easy Vegan Lentil Meatloaf Recipe

Vegan Meatloaf

This meatless version uses beans or grains as a base, with plenty of seasoning and a hearty texture. It’s often topped with a tangy glaze and bakes into a firm loaf that holds its shape. The flavor leans savory with just enough bite from spices and herbs. A great main dish that works year-round.
Get the Recipe: Vegan Meatloaf

Italian Meatloaf

Herbs like oregano and basil, plus garlic and Parmesan, bring an Italian twist to this loaf. It’s often stuffed or topped with mozzarella and finished with marinara instead of the usual glaze. Each slice feels like a mash-up between meatballs and lasagna. Serve it with pasta or roasted vegetables.
Get the Recipe: Italian Meatloaf

Meatloaf with Creamy Onion Gravy

Instead of a glaze, this meatloaf is topped with a generous pour of smooth onion gravy. The sauce adds richness and depth, soaking into each slice as it’s served. It’s a comforting twist that pairs perfectly with mashed potatoes. The texture is soft and savory, ideal for cold nights.
Get the Recipe: Meatloaf with Creamy Onion Gravy

Bomb Meatloaf

This version leans into bold seasoning and rich ingredients, think Worcestershire, garlic, cheese, and a touch of heat. It’s often topped with a sticky, flavorful glaze or melted cheese. The name says it all: this loaf is loud, filling, and made to impress. Great when you want meatloaf with personality.
Get the Recipe: Bomb Meatloaf

Southern Meatloaf Recipe

This take on the classic uses everyday ingredients and leans into comfort with a sweet and tangy glaze. The texture is tender but firm, and the flavor is built from onions, peppers, and spices. It’s straightforward and nostalgic in the best way. Ideal for weeknights or Sunday dinner.
Get the Recipe: Southern Meatloaf Recipe

Stuffed Meatloaf

This loaf has a surprise inside, often cheese, vegetables, or a layer of spinach or mushrooms tucked into the middle. The filling adds moisture and breaks up the texture. Each slice looks as good as it tastes. It’s a small step that makes a big difference.
Get the Recipe: Stuffed Meatloaf

Chicken Parmesan Meatloaf

Ground chicken replaces beef in this Italian-inspired loaf that’s topped with marinara and melted mozzarella. The flavor is lighter but still rich, with breadcrumbs and seasoning keeping the loaf moist. It’s a good change-up when you want something different but still familiar. Best served with pasta or salad.
Get the Recipe: Chicken Parmesan Meatloaf

Meatloaf Casserole

This all-in-one meal combines layers of mashed potatoes, meatloaf, and sometimes vegetables or cheese. Everything bakes together into a warm, hearty casserole. It slices easily and reheats well. A great way to feed a group or turn leftovers into something new.
Get the Recipe: Meatloaf Casserole

Low Carb Meatloaf with Cheese and Leeks

This loaf skips breadcrumbs and instead uses leeks for flavor and moisture. Cheese melts throughout, adding richness without the carbs. The result is dense, savory, and filling without feeling heavy. A solid pick for low-carb eaters who still want a classic meal.
Get the Recipe: Low Carb Meatloaf with Cheese and Leeks

Cracker Barrel Meatloaf

A restaurant copycat made with crackers instead of breadcrumbs, giving it a soft texture and slightly sweet flavor. The glaze is thick and sticky, balancing savory meat with tangy-sweet topping. It’s all about comfort and nostalgia. Serve it with mashed potatoes and green beans for the full effect.
Get the Recipe: Cracker Barrel Meatloaf

Cowboy Meatloaf and Potato Casserole

This meatloaf is topped with mashed potatoes, cheese, and sometimes crispy onions or BBQ sauce. It’s layered like a shepherd’s pie but with a smoky, Southern-style twist. Each bite brings savory meat, creamy potatoes, and melty cheese. Ideal for feeding a hungry crowd.
Get the Recipe: Cowboy Meatloaf and Potato Casserole

Tasty BBQ Smoked Meatloaf with Glaze

Smoked low and slow, this meatloaf absorbs deep wood flavor while staying moist inside. A BBQ glaze coats the outside, creating a flavorful bark. It’s ideal for weekend cooking when you’ve got time and a smoker ready. A bold twist on the traditional loaf.
Get the Recipe: Tasty BBQ Smoked Meatloaf with Glaze

Bacon Cheeseburger Meatloaf

This version loads ground beef with chopped bacon, cheese, and burger-style seasoning. The flavors are familiar but turned up, with a juicy texture and a hint of smoke from the bacon. Toppings like pickles or sauce can add even more burger flair. It’s comfort food in a slice.
Get the Recipe: Bacon Cheeseburger Meatloaf